Being Sick Is Very Expensive

Daily Observer

January 31, 1975

 

 

 

            The miracle of medication has surely prolonged life, and in so doing, inadvertently inflicted hardship on those of us dependent on drugs for an acceptable state of well-being.  Because medicines are very expensive.  The government is finding out what each of us has known for a long time.  Sickness is very expensive.  With increasing government funding of the American bill for health, (estimated at about 80 billion dollars, almost as much as the defense bill) the government is looking for ways to cut costs.  One way, promulgated by Casper Weinberger, secretary of the Department of Health, Education and Welfare, is to permit pharmacists to substitute generic drugs for brand names at their own discretion.

            The reasoning behind this is that after the patients have run out on a medication, its formula is open, and available to all pharmaceutical and chemical companies.  Secondary and tertiary distributors can buy the chemical and distribute it under its generic name.  Thus, Miltown or Equanil become meprobamate, Mellaril is thoridizine, Thorazine is chlorpremazine, Lanoxin is digoxin, and so forth.

            There can be considerable savings in substituting the generic product for the brand name substance.  The only problem is that the company that produced the brand name product and took out the patients, and invested millions of dollars, is one of an infinite number of reputable companies, whose experience with governmental agencies has so sensitized them, that they continually test and retest their products.  They measure shelf-life,  bioavailability, sterility and numerous other factors.

            Doctors tend to prescribe brand name drugs in many instances because they have learned through the years to have faith in their reliability.  If something goes wrong, they can point to the company who made the drug.  If the pharmacist is given license to substitute generics at will, it will be very difficult to trace faulty medications.

            There are several reasons for this.  First, the pharmacist might change his distributor.  Secondly the distributor might have changed his source of medications.  The fact is that anyone can put a label on a bottle, that really doesn’t define the source of the material.  If generic substitution becomes law, patients will demand the generic drug, and demand the cheaper product from the pharmacist.  The pharmacist will be forced to the open market, drug-houses will proliferate like flies, and the quality control upon which the physician has for so long depended, will have evaporated in the cloud of government edict.

            Apparently the patient has run out on Furadantin, made by Eaton Laboratories.  Furadantin, generically known as nitrofurantein can now be made by anybody and sold by anybody.  True these surveyors are fully licensed, but there are not enough government inspectors to keep track of the numerous by-ways and pathways in the forest of chemical produce and distribution.

            Eaton, of course, is upset at the competition.  Its prices for nitrofuantein are considerably higher than those charged by generic wholesalers, probably because it has high overhead, much of which is devoted to producing the product under quality conditions and to maintain a continued surveillance on production and degradation of the formulation; and also, because tax-law makes it prudent to reinvest profits into research so that other drugs as excellent as Fruadantin can be produced.  For whatever the reason, however, Eaton has sent out a flyer, which is a copy of a brochure put out by the Food and Drug Administration, called FDA Report of Recalls.  It makes interesting reading.

            In brief:

            Nitrofurantein tabs; made by Rachell, recalled because of sub potency.

            Chorienic gonadeptrophin; Hallmark; Labeling error.

            Lidecaine HC1 Injectable; USP; by Preme Pharmaceutical Lags; Labeling mix-up

            Nitrofurantein tables; USP; Caribe Chemical Co.; Virgin Islands; cross contamination (with another chemical).

            Medicated Bandage; Sterile; McClinteck’s Lab; Non-sterile.

            The list continues with more of the same.  There is subpotent digitalis, aminiphyllin that fails the dissolution test, injectable hydrocortisone that failed tests for sterility, and baby shampoo contaminated with pseudomonas aeruginosa bacteria.

            Perhaps Eaton has excluded some of the recalls, or omitted recalls from well-known companies.  It is possible.  But the point is, that if generics proliferate and the physician’s right to prescribe that which he believes to be best for the patient is denied, federal agents the size of an army will be required to track down medications that may be inadequate for the job they are intended to do.  The cost of the army of inspectors alone will probably drive the cost of the medication up to its original brand-name cost.  The government is setting free forces that it may not be able to control.  The public should beware of this gamble, and the best way to protect itself is to inform itself.